From Downtown Charleston:

Head west on Calhoun Street
Continue onto SC-30 West
Turn right onto Folly Road
Turn Left onto Crosscreek Drive
Cross Creek Walk will be on your right

From the Charleston International Airport:

Head south on I-526 West
Turn left onto US-17 N.
Turn right onto Wesley Drive
Continue straight onto Folly Road Blvd.
Turn right onto Crosscreek Drive
Cross Creek Walk will be on your right